Adenomyosis as a Barrier to Effective Surgery for Dyspareunia in Rectovaginal Endometriosis

Adenomyosis as a Barrier to Effective Surgery for Dyspareunia in Rectovaginal Endometriosis By Selma Oransay

Women with endometriosis often experience severe pain during intercourse, known as dyspareunia, which can deeply affect their quality of life and intimate relationships. One form of this condition, rectovaginal septum endometriosis, involves deep, scarred tissue that can cause pain during…

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Nerve-Sparing Surgery Safe in DIE

Nerve-Sparing Surgery Safe in DIE By Özge Özkaya

Robot-assisted nerve-sparing modified radical hysterectomy is associated with longer operative times and lower estimated blood loss compared to the conventional laparoscopic approach to treat deep infiltrating endometriosis (DIE), according to a new study published in the scientific journal Archives of…

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Conventional Laparoscopy as Good as Robotic-Assisted Laparoscopy

Conventional Laparoscopy as Good as Robotic-Assisted Laparoscopy By Özge Özkaya

Both conventional laparoscopy and robotic-assisted laparoscopy are associated with significant long-term symptom relief in patients with endometriosis involving the sacral plexus and sciatic nerve, according to a new study published in the International Journal of Gynecology & Obstetrics. “Although surgeons…

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Impact of Endometriosis Subtypes on Increased Ovarian Cancer Risk

Impact of Endometriosis Subtypes on Increased Ovarian Cancer Risk By Özge Özkaya

The risk of ovarian cancer is markedly increased in patients with ovarian endometriomas and/or deep infiltrating endometriosis (DIE), according to a new study published in The Journal of the American Medical Association.  These patients should be offered counseling about the risk of ovarian cancer and…

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MRI Improves Deep Infiltrating Endometriosis Diagnosis

MRI Improves Deep Infiltrating Endometriosis Diagnosis By Özge Özkaya

Magnetic resonance imaging (MRI) with susceptibility-weighted imaging sequence is the best method of non-invasively diagnosing endometriosis, according to a new study published in the International Journal of Reproductive BioMedicine. However, the authors noted, “Laparoscopy is still the gold standard of…

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Early diagnosis of deep infiltrating endometriosis in adolescence

 Early diagnosis of deep infiltrating endometriosis in adolescence By Selma Oransay

Dysmenorrhea is widely observed in adolescence, and endometriosis is one of its causes. However, endometriosis diagnosis is usually made after 25 years of age. It is clear that early diagnosis and management of this progressive disease is essential and will…

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Can We Reliably Measure Sleep Quality in Women With Endometriosis?

Can We Reliably Measure Sleep Quality in Women With Endometriosis? By Özge Özkaya

The Insomnia Severity Index (ISI) and the Pittsburgh Sleep Quality Index (PSQI) lead to consistent scores comparable in women with deep infiltrating endometriosis, according to a new study published in the scientific journal Sleep Medicine. However, the cutoff values of…

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Surgery Pivotal in Improving Quality of Life in Endometriosis Patients

Surgery Pivotal in Improving Quality of Life in Endometriosis Patients By Özge Özkaya

Surgery plays a pivotal role in improving the quality of life of women with endometriosis who have previously not responded to medical therapy. This is according to a new study published in the Journal of Minimally Invasive Gynecology. During the…

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Cells Constituting Endometriosis Have Different Properties

Cells Constituting Endometriosis Have Different Properties By Özge Özkaya

Many cell types are altered in endometriosis, found a new study published in the Journal of Pathology. The study also found that depending on the subtype of endometriosis, endometriosis cells show signatures of estrogen responsiveness, immunologic cytotoxicity, and proinflammation. Finally, it identified…

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Diagnosis and the Treatment of Postmenopausal Endometriosis

Diagnosis and the Treatment of Postmenopausal Endometriosis By Selma Oransay

About 190 million women around the world are diagnosed with endometriosis. The majority of the cases are between 30 and 40 years of age. After menopause, the incidence of endometriosis declines to 2-5%, and it is more common in women…

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Potential New Therapeutic Avenue for Deep Endometriosis

Potential New Therapeutic Avenue for Deep Endometriosis By Özge Özkaya

The use of lipid nanoparticles carrying methotrexate seems to be safe and feasible in women with deep infiltrating endometriosis, according to a new study published in the scientific journal Archives of Gynecology and Obstetrics. The approach could, therefore, be a new…

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A pioneering study on clinicopathologic features of biopsies of endometriotic lesions

A pioneering study on clinicopathologic features of biopsies of endometriotic lesions By Nasuhi Engin Aydin

Deep infiltrating endometriosis, where endometriotic lesions have an invasion depth of ≥5mm to the underlying tissues, is well known due to the troublesome features, peritoneal endometriosis is very common and widely distributed by superficial involvement in the pelvic visceral and…

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Preoperative flexible sigmoidoscopy in patients with deep infiltrating endometriosis

Preoperative flexible sigmoidoscopy in patients with deep infiltrating endometriosis By Hale Goksever Celik

Deep infiltrating endometriosis is defined as endometriotic lesions extending 5 mm or more below the peritoneal surface. Women with deep endometriosis have rectovaginal lesions affecting the tissue adjacent to, or directly involving the rectum and/or rectosigmoid colon with a 90%…

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Does ZEB1 Gene Expression Govern Endometriosis Infiltration Pattern?

Does ZEB1 Gene Expression Govern Endometriosis Infiltration Pattern? By Özge Özkaya

The expression of a gene called ZEB1 is different between different types of endometriosis, found a new study published in the European Journal of Obstetrics & Gynecology and Reproductive Biology. This could affect whether or not lesions become infiltrative.   More importantly,…

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A Starch-Based Gel Barrier Reduces Pain and Improves Fertility After Endometriosis Surgery

A Starch-Based Gel Barrier Reduces Pain and Improves Fertility After Endometriosis Surgery By Özge Özkaya

The development of pain was reduced in women with endometriosis who underwent surgery for deep infiltrating endometriosis (DIE) resection and the "gel barrier 4DryField® PH" was used during the operation, according to results from a randomized controlled trial. Moreover, fertility was improved. "4DryField® PH"…

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Another New Approach Could Help Diagnose deep Infiltrating endometriosis

Another New Approach Could Help Diagnose deep Infiltrating endometriosis By Özge Özkaya

Elastography could help distinguish deep infiltrating endometriosis (DIE) nodules from non-endometriotic tissue at different locations, according to a new study published in Ultraschall in der Medizin - European Journal of Ultrasound. The potential of the technique in improving the diagnosis…

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Deep Infiltrating Endometriosis and Adenomyosis have different genetic pathways

 Deep Infiltrating Endometriosis and Adenomyosis have different genetic pathways By Bahar Yuksel

It is still not defined whether adenomyosis is also a deep endometriosis component or not. In the study conducted by Marshall et al, the researchers compared the gene expression patterns between deep infiltrating endometriosis (DIE) and adenomyosis uteri in order…

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A Multidisciplinary Surgical Team Is a Must in Deep Endometriosis Surgery

A Multidisciplinary Surgical Team Is a Must in Deep Endometriosis Surgery By Özge Özkaya

Endometriosis must be managed by a team of multidisciplniary specialists, especially in case it causes damage to the digestive tract, according to a new study published in the journal Archives of Gynecology and Obstetrics. According to the authors, the presence…

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A review of multimodal imaging modalities for endometriosis.

A review of multimodal imaging modalities for endometriosis. By Selma Oransay

Since there is a lack of non-invasive biomarkers to diagnose endometriosis clinically, imaging techniques such as transvaginal ultrasonography and MRI have significant importance in preoperative endometriosis diagnosis. These imaging techniques allow appropriate surgical planning before laparoscopic excision, especially in deeply…

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Postoperative pregnancy outcomes in women with deep infiltrating endometriosis

Postoperative pregnancy outcomes in women with deep infiltrating endometriosis By Hale Goksever Celik

Subperitoneal invasion of endometriotic lesions exceeding 5 mm in depth is named "deep infiltrating endometriosis' and can be located on uterosacral ligaments, in the intestine, vagina, bladder, and ureter. Women with deep infiltrating endometriosis suffer from pelvic pain and infertility most…

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The emotions and experiences of women with endometriosis during and after pregnancy

The emotions and experiences of women with endometriosis during and after pregnancy By Eylül GÜN

It is well-known that endometriosis patients have a high rate of infertility and a hard time getting pregnant compared to women without endometriosis. Despite the belief that pregnancy can alleviate endometriosis symptoms, some studies have shown that women with endometriosis…

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 How accurate is ultrasonography in evaluating deep infiltrating endometriosis?

 How accurate is ultrasonography in evaluating deep infiltrating endometriosis? By Eylül GÜN

Deep infiltrating endometriosis (DIE) appears to be the most severe form of endometriosis comprising 15-30% of all endometriosis patients. The difference in the presentation of the lesions ranges from simple adhesions to infiltrative nodules. Even though there is no consensus…

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Does endometrioma size have an effect on IVF/ICSI outcomes?

Does endometrioma size have an effect on IVF/ICSI outcomes? By Hale Goksever Celik

Assisted reproductive technologies including IVF/ICSI can be suggested as the therapeutic option in women with endometriosis-associated infertility. In literature, there is a controversy regarding the influence of endometrioma size on IVF/ICSI outcomes. The group led by Drs Chapron and Santoulli…

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Study Identifies Factors Associated With Risk of UrinaryTract Endometriosis Recurrence

Study Identifies Factors Associated With Risk of UrinaryTract Endometriosis Recurrence By Özge Özkaya

Being younger than age 25 and having an autoimmune disease are significant predictors of the recurrence of urinary tract endometriosis after surgery according to a new study published in the Journal of Minimally Invasive Gynecology. Adjuvant hormonal therapy, on the…

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Transvaginal Ultrasound Could Be Sufficient to Properly Diagnose Deep Endometriosis and Ovarians Endometriomas

Transvaginal Ultrasound Could Be Sufficient to Properly Diagnose Deep Endometriosis and Ovarians Endometriomas By Özge Özkaya

Following the International Deep Endometriosis Analysis consensus can improve the accuracy of transvaginal ultrasound to diagnose ovarian endometriomas and deep infiltrating endometriosis, according to a new study published in the scientific journalUltrasound in Obstetrics & Gynecology. “ (…) at this…

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Who Is Diagnosing my Endo?

Who Is Diagnosing my Endo? By Özge Özkaya

It is possible to acquire the skills necessary to diagnose endometriosis lesions as well as adenomyosis using three-dimensional rectosonography after a short learning period in an expert radiology center. This is according to a new study by French researchers published…

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Comparison of imaging techniques for estimating the depth of bowel wall infiltration by endometriosis.

Comparison of imaging techniques for estimating the depth of bowel wall infiltration by endometriosis. By Selma Oransay

The surgical removal of deep endometriosis is the cornerstone of the management. However, the decision for the varying surgical approach types ranging from conservative management (shaving) to segmental or discoid resection depends on the depth of infiltration within the bowel wall, which…

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Imaging Techniques Able to Predict Depth of Endometriosis Before Surgery

Imaging Techniques Able to Predict Depth of Endometriosis Before Surgery By Özge Özkaya

Transvaginal ultrasound (TVUS) and pelvic magnetic resonance imaging (MRI) performed by a specialist can accurately predict the depth of rectosigmoid endometriosis before surgery, according to a new study published in the Journal of Minimally Invasive Gynecology. Both approaches are similar…

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Effects of Bowel Endometriosis Surgery on Mode of Delivery

Effects of Bowel Endometriosis Surgery on Mode of Delivery By Özge Özkaya

Less than a third of doctors counsel women about the possible effects of surgical treatment of bowel endometriosis on their mode of delivery should they become pregnant, according to a new study published in the Journal of Obstetrics and Gynaecology.…

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How Likely Am I to Conceive After Endometriosis Surgery?

How Likely Am I to Conceive After Endometriosis Surgery? By Özge Özkaya

Women with superficial peritoneal endometriosis and just one type of lesion are more likely to conceive after surgery, according to a new study published in the International Journal of Gynecology and Obstetrics.  This is important because patients will be better…

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Does Surgery Improve the Digestive Symptoms of Endometriosis?

Does Surgery Improve the Digestive Symptoms of Endometriosis? By Özge Özkaya

Women with deep infiltrating endometriosis involving the bowels have the most significant improvement in gastrointestinal symptoms following surgery. This is according to the findings of a comparative retrospective study in almost 1,500 women.  “Women with severe bowel symptoms and deep…

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Technical Facts for the Prevention of Complications After Deep Endometriosis Surgery

Technical Facts for the Prevention of Complications After Deep Endometriosis Surgery By Özge Özkaya

There are no differences in the risk of rectovaginal fistula in women with rectovaginal endometriosis who were managed by a liberal or restrictive policy of preventive stoma according to a study by French researchers published in the Journal of Minimally…

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Impact of adenomyosis on sexual life

Impact of adenomyosis on sexual life By Selma Oransay

Considering the similar etiopathogenesis and pain symptoms between adenomyosis and deep infiltrating endometriosis, Alcalde et al. from the Department of Gynecology, University of Barcelona, Spain, aimed to call attention to the presence of potential sexual dysfunction not only in patients with deep…

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How Does Endometriosis Affect Patients Quality of Life?

How Does Endometriosis Affect Patients Quality of Life? By Özge Özkaya

Health-related quality of life is significantly lower in patients with endometriomas or deep infiltrating endometriosis compared to women without the disease. This is according to the results of a recent study in adult Spanish women that was published in the "International…

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Adhesion Barrier Helps After Endometriosis Surgery

Adhesion Barrier Helps After Endometriosis Surgery By Özge Özkaya

An adhesion barrier, named "4DryField® PH" significantly reduced the formation of adhesions following endometriosis surgery, according to a new study by German scientists.  The formation of adhesions following endometriosis surgery is a severe problem that affects 90% of patients. The…

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Endometriosis Surgery Improves Sex Life

Endometriosis Surgery Improves Sex Life By Özge Özkaya

Women who underwent laparoscopic resection surgery to treat their deep infiltrating endometriosis had improved sexual quality of life and health-related quality of life according to a new study published in the Journal of Minimally Invasive Gynecology. These findings are important…

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Improvement of the quality of life after surgery for deep infiltrating endometriosis.

Improvement of the quality of life after surgery for deep infiltrating endometriosis. By Selma Oransay

Deeply infiltrating endometriosis is the most severe form among the endometriosis types. The required laparoscopic approach is the appropriate excision of endometriotic foci from pelvis, by consideration of failure and side effects of the medical treatments. The specialist endometriosis centers…

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Postoperative pregnancy rate in infertile women with deep infiltrating endometriosis

 Postoperative pregnancy rate in infertile women with deep infiltrating endometriosis By Hale Goksever Celik

Deep infiltrating endometriosis (DIE) is fibrous/muscular infiltration of organs and anatomical structures containing endometrial tissue below the peritoneum regardless of the depth of infiltration. Another definition describes DIE as infiltration of the peritoneum by endometriotic lesions deeper than 5 mm. Pain,…

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Urological Challenges in Endometriosis Surgery - Guenter Noe, MD

Urological Challenges in Endometriosis Surgery - Guenter Noe, MD By Özge Özkaya

In this presentation, Dr. Guenter Noé, Head of Department of Rheilandklinikum Dormagen in Germany talks about endometriosis affecting the urinary tract. Dr. Noé starts by describing the different parts of the urinary tract that can be affected by endometriosis including…

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Deep Endometriosis or Recto-uterine Obliteration Without Endometrioma

Deep Endometriosis or Recto-uterine Obliteration Without Endometrioma By Selma Oransay

The diagnostic help of ultrasound is increasing by its ability to diagnose deep infiltrating and rectouterine pouch obliteration in patients who are suffering from chronic pelvic pain. Clinicians are used to evaluating the rectal and parametrial areas of the endometriotic…

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Prevalence, Risk factors and Management of Bowel Fistula after Rectosigmoid Surgery for Deep Endometriosis

Prevalence, Risk factors and Management of Bowel Fistula after Rectosigmoid Surgery for Deep Endometriosis By Selma Oransay

Bowel fistula is a severe complication after the colorectal endometriosis surgery, but little is known about its prevalence, and reports on large series are lacking. To discuss specific management on colorectal deep endometriosis, Roman et al. conducted a retrospective study…

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Endometriosis surgery and future pregnancy complications

Endometriosis surgery and future pregnancy complications By Selma Oransay

Endometriosis is one of the known diseases for infertility in the reproductive period of women. Several studies revealed that endometriosis itself maybe the reason for some unfavorable obstetric outcomes. Localization, the type of endometriotic lesions, and the stage of endometriosis…

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Risk Factors Associated with Ureteral Endometriosis

Risk Factors Associated with Ureteral Endometriosis By Özge Özkaya

Patients with severe endometriosis, uterosacral ligament deep involvement with endometriosis lesions of  3 cm in diameter or more, and the presence of previous endometriosis surgery have a significantly higher risk of having ureteral endometriosis. This is according to a study…

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Transvaginal sonography for predicting the distance between rectosigmoid endometriosis and the anal verge

Transvaginal sonography for predicting the distance between rectosigmoid endometriosis and the anal verge By Timur Seckin

For optimal surgery, pre-surgical assessment of the distance between rectosigmoid deep endometriosis lesions and the anal verge (Lesion to Anal Verge Distance-LAVD) is recommended by many specialists. A group of researchers from Norway, Austria, and Australia studied the accuracy of…

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Recurrence following surgery for subtypes of endometriosis

Recurrence following surgery for subtypes of endometriosis By Hale Goksever Celik

Endometriosis is a disease identified by the location of endometrial stromal and glandular cells outside the uterine cavity. It is considered as a gynecological disease of reproductive-aged women. Three subtypes of endometriosis are peritoneal endometriosis which defines the endometriotic lesions…

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A Routine Pelvic Ultrasound Examination Should Include an Evaluation for Endometriosis

A Routine Pelvic Ultrasound Examination Should Include an Evaluation for Endometriosis By Özge Özkaya

Routine pelvic ultrasound examination should be extended beyond the uterus and ovaries into the posterior and anterior pelvic compartments, according to Australian doctors.  With such examinations, deep infiltrating endometriosis nodules can be searched, say the authors, allowing women to be…

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Does Getting Pregnant Really Help When You Have Endometriosis?

Does Getting Pregnant Really Help When You Have Endometriosis? By Özge Özkaya

Pregnancy has a favorable impact on the volume of deep infiltrating endometriosis lesions according to a study published in the scientific journal "PLoS One". This is the first study that demonstrates such a favorable impact of pregnancy on endometriosis lesion…

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Surgery and the endometriosis associated-pain: A systematic review

Surgery and the endometriosis associated-pain: A systematic review By Selma Oransay

The surgical approach for pelvic pain-related to endometriosis depends on the stage and the type of the endometriotic lesion and ranging from ablation and the excision of the lesions to radical surgery as hysterectomy with removal of ovaries and presacral…

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MRI findings predicting the need for colorectal surgical treatment of deep infiltrating endometriosis

MRI findings predicting the need for colorectal surgical treatment of deep infiltrating endometriosis By Irem Onur

LAY SUMMARY: Brusic A. et al., a group of researchers from Australia, conducted a retrospective study to identify the features of deep infiltrating endometriosis on MRI which have an association with colorectal surgical bowel resection. They have recently published their…

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Is deep infiltrating rectosigmoid endometriosis a progressive disease?

Is deep infiltrating rectosigmoid endometriosis a progressive disease? By Demet Candaş Green

This study by Netter at al., published in "Human Reproduction" in November 2019 aimed to assess the risk of progression of deep endometriotic nodules infiltrating the rectosigmoid and to evaluate the influence of continuous amenorrhoea (absence of menstruation) on the development…

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Which Diagnosis Technique is Better?

Which Diagnosis Technique is Better? By Özge Özkaya

Transvaginal ultrasound provides a more accurate localization of vaginal and recto-vaginal endometriosis compared to magnetic resonance imaging (MRI) according to a study published in the International Journal of Gynecology & Obstetrics. However, MRI has better accuracy in detecting bladder endometriosis…

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The postoperative functional outcomes of deep infiltrating endometriosis

The postoperative functional outcomes of deep infiltrating endometriosis By Hale Goksever Celik

Rectosigmoid endometriosis is defined as the infiltration of the bowel wall with the endometrial-like glands and stroma, reaching at least the muscular layer. The most commonly involved sites are the rectum and sigmoid colon. For the management of deep infiltrating…

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The coexistence deep infiltrating endometriosis and fibromyalgia

The coexistence deep infiltrating endometriosis and fibromyalgia By Hale Goksever Celik

Endometriosis is defined as the localization of endometrial glandular and stromal cells outside the uterine cavity. The main symptoms of endometriosis which are dysmenorrhea, dyspareunia, and chronic pelvic pain impair the quality of life of these women. This disease may…

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Can early-life exposures affect endometriosis development later in life?

Can early-life exposures affect endometriosis development later in life? By Demet Candaş Green

Endometriosis is a complex disease with possible multifactor contributors. So far, inflammatory, immunogenic, genetic, and environmental factors have all been associated with endometriosis. In addition, it is possible that different types of endometriosis lesions – peritoneal, ovarian, and deep infiltrating…

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Somatic mutations in iatrogenic endometriosis.

Somatic mutations in iatrogenic endometriosis. By Selma Oransay

Lac and al., from the Department of Molecular Oncology in BC Cancer Research Center, Vancouver, Canada, planned a retrospective and multinational research to investigate the prevalence of somatic cancer-driver mutations in incisional endometriosis and recently published in the "Journal of Human Reproduction". Their…

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Further Results From the FEELING Study Published

Further Results From the FEELING Study Published By Özge Özkaya

Some women are more likely to develop deep infiltrating endometriosis according to the further analysis of the results of the FEELING study. These are women who: are married, are older,  have siblings,  have had a prior pregnancy,  or for whom…

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The diagnosis and management of endometriosis in Korea

The diagnosis and management of endometriosis in Korea By Selma Oransay

The Korean Society of Endometriosis has scrutinized the present published literature of endometriosis in the domestic and international platform to provide new guidelines and the clinical management of the disease. The study was recently published in the journal "Obstetrics and Gynecology…

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Can MRI be used to detect anterior pelvic endometriotic lesions?

Can MRI be used to detect anterior pelvic endometriotic lesions? By Hale Goksever Celik

Deep infiltrating endometriosis is the most severe manifestation of endometriosis. It is defined as the infiltration of ectopic endometrial tissue under the peritoneum, pelvic structures, and the organ walls such as the uterosacral ligaments, colon, vagina, bladder, ureter, rectovaginal septum,…

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Does deep infiltrating endometriosis affect sexual activity?

Does deep infiltrating endometriosis affect sexual activity? By Dr. Youngran Park

Endometriosis is one of the most common gynecological diseases in women of reproductive age, and pelvic pain and infertility are the most frequent complications. There are three different type of endometriosis lesions; superficial lesions, deep lesions, and ovarian cysts. In…

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Anatomic distribution of endometriosis

Anatomic distribution of endometriosis By Irem Onur

In the study of Audebert et al. which has been published in the journal European Journal of Obstetrics and Gynecology, the anatomic distribution of endometriosis, the rate of deep infiltrating endometriosis during the various study periods, laterality of endometriosis, pelvic…

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Parametrial endometriosis: A harder form of endometriosis

Parametrial endometriosis: A harder form of endometriosis By Hale Goksever Celik

Deep infiltrating endometriosis is the most severe manifestation of endometriosis, affecting 20% of all patients with endometriosis. It is defined as the infiltration of ectopic endometrial tissue under the peritoneum, pelvic structures, and the organ walls such as the uterosacral…

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Will I Have Complications After Endometriosis Surgery?

Will I Have Complications After Endometriosis Surgery? By Özge Özkaya

The rate of complications after surgery to treat deep infiltrating endometriosis is low, confirmed a study by researchers in Germany. It is important to know whether major or minor complications following surgery are likely to develop and what the outcome…

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Laparoscopic surgery of endometriosis through three compartments

Laparoscopic surgery of endometriosis through three compartments By Selma Oransay

This case study which is published in the J. of Minimally İnvasive Gynecology is the video demonstration of Collin et al who performed the laparoscopic operation of their patient in Gynecologic Surgery Department of Strasburg Hospital University, France. 37 years old…

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IVF Is the Best Option to Become Pregnant for Women with Severe Endometriosis, or Is It Not?

IVF Is the Best Option to Become Pregnant for Women with Severe Endometriosis, or Is It Not? By Özge Özkaya

Treating rectal endometriosis with surgery seems to increase the chance of a woman conceiving, with most pregnancies occurring naturally. This is according to a study published in the medical journal Human Reproduction.  The optimal treatment for women with severe endometriosis…

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Endometrioma and endometriosis

Endometrioma and endometriosis By Irem Onur

Exacoustos C. et al. published an article titled “The isolated ovarian endometrioma: a history between myth and reality” in the Journal of Minimally Invasive Gynecology in 2018. They aimed to examine the association between ovarian endometriomas detectable at the transvaginal ultrasound…

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How to evaluate ureteral endometriosis : A review of the literature

How to evaluate ureteral endometriosis :  A review of the  literature By Selma Oransay

In this recently published review of the literature, Barra et al. from Genova, Italy intend to provide a useful tool to guide physicians in the management of deep infiltrating endometriosis. Authors elected 67 abstracts from Pubmed and Medline in accordance with PRISMA…

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Fluorescence Guided Surgery: a New Technique to Treat Deep Infiltrating Endometriosis

Fluorescence Guided Surgery: a New Technique to Treat Deep Infiltrating Endometriosis By Özge Özkaya

Fluorescence-guided surgery could help differentiate recto-vaginal deep infiltrating endometriosis nodules (RVDIEN) from healthy rectal tissue and remove them successfully without perforating the rectum, according to a study published in the scientific journal Surgical Innovation.  The method could offer a better,…

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Deep Infiltrating Endometriosis Impairs Sexual Function

Deep Infiltrating Endometriosis Impairs Sexual Function By Kasthuri Nair

Lima et al., a group of scientists from Hospital do Servidor Público Estadual in Brazil, recently published an article entitled “Female Sexual Function in Women with Suspected Deep Infiltrating Endometriosis” in Revista Brasileira De Ginecologia E Obstetricia. The paper analyzed…

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Recurrence of Deep Infiltrating Endometriosis

Recurrence of Deep Infiltrating Endometriosis By Yu Yu

There are mainly three types of endometriotic lesions. These are ovarian endometriosis, superficial peritoneal endometriosis, and deep infiltrating endometriosis (DIE). The latter is often described as a lesion with greater than 5 mm invasion of the peritoneal surface. DIE lesions…

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MRI Best at Detecting Intestinal Deep Infiltrating Endometriosis

MRI Best at Detecting Intestinal Deep Infiltrating Endometriosis By Özge Özkaya

Magnetic resonance imaging (MRI) seems to be a better method in identifying deep infiltrating endometriosis in the intestine compared to two-dimensional ultrasonography (2DUS), found a study by researchers in Italy and Spain. However, this does not seem to be the…

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Fetal Membranes Abnormalities in Pregnant Women with DIE

Fetal Membranes Abnormalities in Pregnant Women with DIE By Kasthuri Nair

Marcellin, Méhats, and Gogusev formulated a study where they analyzed alterations in the fetal membranes (FM) of women suffering from severe endometriosis. Their paper titled “Histopathological Alterations in Fetal Membranes of Women With Endometriosis” was recently published in the Reproductive…

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Women with Deep Infiltrating Endometriosis Have a Higher Risk of Appendix Involvement

Women with Deep Infiltrating Endometriosis Have a Higher Risk of Appendix Involvement By Özge Özkaya

Women with deep-infiltrating endometriosis, a form of endometriosis that invades the abdominal and pelvic cavity, have an increased risk of developing endometriosis of the appendix. It is therefore important to check women with deep infiltrating endometriosis for appendix involvement during…

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Ovarian Endometriomas vs Deep Infiltrating Endometriosis

Ovarian Endometriomas vs Deep Infiltrating Endometriosis By Yu Yu

Ovarian endometrioma (OMA) and deep infiltrating endometriosis (DIE) have been described as two disease entities, although they are both characterized by endometrial tissue located outside the uterus. As OMA and DIE look different histologically, it is puzzling what cause their…

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Bowel Involvement in Deep Infiltrating Endometriosis

Bowel Involvement in Deep Infiltrating Endometriosis By Özge Özkaya

Cleansing the colon before an ultrasound makes it easier to detect rectal nodules of deep infiltrating endometriosis, found a study published in the Journal of Minimally Invasive Gynecology.  Cleansing the colon before a surgery is called bowel preparation and is…

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Deep Infiltrating Endometriosis, Surgery and Fertility

 Deep Infiltrating Endometriosis, Surgery and Fertility By Kasthuri Nair

Carneiro, Costa, and Ávila recently published an article in a scientific journal named Reproduction, titled “To operate or not to operate on women with deep infiltrating endometriosis (DIE) before in vitro fertilization (IVF),” that explored the relationship between DIE and infertility.…

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A potential indicator of invasive endometriosis. 

A potential indicator of invasive endometriosis.  By Asli Bahadirli Talbott

Furuya & Masuda et al., in their recent article that will be published in Acta Obstet Gynecol Scand, report that the protein encoded by ZEB1 gene (Zinc finger E-box-Binding homeobox) is a potential indicator of invasive endometriosis.  ZEB1 is a transcription factor that has been implicated…

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Unexpected "cancer-related" mutations in "non-cancerous" endometriosis: Do they predict aggressiveness?

Unexpected By Laura Ardighieri

A study supported by Endometriosis Foundation of America, reported by scientists from Johns Hopkins Medicine (Baltimore, USA) and the University of British Columbia (Vancouver, Canada) have identified the molecular alterations of deep infiltrating endometriosis trough a wide exome­ sequencing (protein-coding genetic alphabet…

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